GIPR COS7
CBP71671
询 价
索取Protocol
产品描述
产品数据库
| I. Background | |
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G 蛋白偶联受体(GPCR) 是跨膜蛋白受体，其特征是配体数量可变，包括内源性神经递质和激素，也包括外源性天然和人工化合物。激动剂与受体结合后会触发信号通路的激活；而拮抗剂则会阻碍激动剂介导的受体激活。反向激动剂除像拮抗剂一样干扰激动剂外，还会抑制受体的组成活性。 |
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| II. Description | |
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GIPR COS7细胞药靶模型很好的模拟了体内 GIPR的信号转导过程 。 |
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| III. Introduction | |
| Expressed gene: | GIPR |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM + 10%FBS + 400 μg/ml G418 |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional assay for GIPR |
| Transducer: | Gs |
IV. Representative Data Figure 1. HTRF cAMP Assay with GIPR COS-7(C30). |
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